The major and minor grooves are opposite each other, and each runs continuously along the entire length of the DNA molecule. They arise from the antiparallel arrangement of the two backbone strands. Note that the grooves are actual structural features of the molecule, not consequences of the way it is drawn. The grooves are important in the attachment ofDNA Binding Proteins involved in replication and trascription.
Thursday, 7 May 2015
Wednesday, 6 May 2015
BCH310 TUTORIAL QUESTIONS
|
UNIVERSITY OF BUEA ONLINE STUDENT ASSOCIATION (UBOSA)
COORDINATOR: LOKENDO T. DEPT:
BIOCHEMISTRY AND MOLECULAR BIOLOGY
COURSE CODE: BCH 310
COURSE TITLE GENETICS
TUTORIAL SESSION
5
Date: Thursday 7th May 2015 Time: 8-11am
Motto: Thinking out of the box for
excellence
|
1) What do you understand by each of the
following?
I.
Chromosomal aberration.
II.
Synonymous mutation.
2) What is genetics? Give importance of
genetics.
3) Distinguish between the following pairs
I.
Euchromatin and heterochromatin.
II.
Constitutive and facultative heterochromatin.
4) What do you understand by the melting point
of DNA?
5)
What is
the melting point of a double stranded DNA molecule that contains
I.
27% GC?
II.
56% GC?
6) Name the major helical conformations of
DNA.
7)
What do
you understand by major and minor grooves with respect to DNA structure?
8) What are the Watson and Crick base pairs?
Why are they important?
9) Consider the following molecules: Guanine (G);
Adenine(A); Uracil(U); Thymine(T); Cytosine(C) and the following properties:
I.
Possesses at least a hydroxyl function.
II.
Possesses an amine function.
III.
Does not contain an oxygen atom.
IV.
Possesses a methyl group
V.
Can base pair wit adenine
VI.
Is a purine base.
VII.
Is a pyrimidine base.
Associate to each molecule, the number(s)
of the property(s) that is (are) applicable to it.
10) Is the intracellular messenger cAMP a
nucleoside or a nucleotide?
11) Match the following list of scientists against
their discoveries
|
Scientists
|
Discoveries
|
|
12)
Darwin and Wallace
|
I.
Genes linearly arranged on some chromosomes
and mapped.
|
|
13)
TH Morgan
|
II.
Related “genes” to enzymes and biochemical
processes
|
|
14)
Sutton Boveri
|
III.
Chromosomal theory of inheritance
|
|
15)
Gregor Mendel
|
IV.
Theories of acquisition of inheritable traits
|
|
16)
Friedrich Miescher
|
V.
Theories of evolution
|
|
17)
Beadle and Tatum
|
VI.
Came up with a central dogma (DNAàmRNAàProteins)
|
|
18)
AH Sturtevant
|
VII.
Theories of transmission of traits
|
|
19)
Oswald Avery x
|
VIII.
Identified DNA in 1869
|
|
20)
Watson, Crick, Franklin & Wilkins
|
IX.
Genes on chromosomes
|
|
21)
Lamarck
|
X.
DNA was the genetic material
|
22) Give one example of each mutagens and
briefly describe how it increases the rate of mutagenesis:
II.
A DNA-modifying chemical
III.
A base analog
23) a) If the GC content of a DNA molecule is
24%, what are the percentages of the four bases (A, G, C, and T) in the
molecule?
b) What is the melting temperature of this DNA?
Good Luck
“Remember,
when you read, you skim the surface, but when you study, you discover the
treasure”
WELCOME TO THE UNIVERSITY OF BUEA ONLINE STUDY ASSOCIATION.
NOTE; IT IS ADVISABLE TO GO THROUGH QUESTION 69-82 IN THE SEMESTER EXAMINATION IN JULY 2011, THAT IS THE SECTION I OF THE PASS QUESTIONS AND ANSWERS WE HAVE. WE WILL LOOK AT THIS IN THE TUTORIAL SESSIONS.
THE ANSWERS BELOW CORRESPONDS TO ONLY Mr. BOYO'S MCQ QUESTIONS RANGING FROM 1-207.
CLICK FOR DEFINITIONS
dishomogenesis
dysplasia
immunoassay
bioassay
THE ANSWERS BELOW CORRESPONDS TO ONLY Mr. BOYO'S MCQ QUESTIONS RANGING FROM 1-207.
CLICK FOR DEFINITIONS
dishomogenesis
dysplasia
immunoassay
bioassay
UPDATED AND CORRECTED MLT302 MULTIPLE CHOICE ANSWERS
PLEASE THIS ANSWERS HAVE JUST BE UPDATED AND CORRECTED Answers for Mr.BOYO'S MCQ questions 1-206
115. C
116.A
117.E
118. B a prohormone is the inactive form of a hormone.
119. B
120.A
121. B
122. B
123. A
124.
125.A
126. A
127. B
128.B
PLEASE FOR NOW THIS IS WHAT HAVE BEEN UPLOADED......................................................................................................
STAY IN TOUCH WITH UBOSA AND MAKE THE BEST OUT OF YOUR LIFE
JESUS LOVES YOU
POSTED BY; Mr. Batenchong Simon Ebaieyong. personal adviser to the president and to the association
- C
- C
- B
- B
- D
- B
- C
- C
- D
- D
- C
- C
- E
- A
- E
- A
- B
- B
- B
- B
- B
- B
- B
- D
- A
- B
- A
- A
- B
- C
- E
- E
- D
- B
- B
- B
- B
- B reasoning; exogenous= from therapy( outside), endogenous= from within
- B
- B
Dishomogenesis is the improper pdtion and secretion of hormones - B Dysplasia is improper development of organs resulting in other effects
- A
- A
- B
- B
- B
- B
- A
- B
- D
- A
- B CBG= Corticosteriod-binding globulin
- B cortisol is a small molecule
- B
- B
- B
- B
115. C
116.A
117.E
118. B a prohormone is the inactive form of a hormone.
119. B
120.A
121. B
122. B
123. A
124.
125.A
126. A
127. B
128.B
PLEASE FOR NOW THIS IS WHAT HAVE BEEN UPLOADED......................................................................................................
STAY IN TOUCH WITH UBOSA AND MAKE THE BEST OUT OF YOUR LIFE
JESUS LOVES YOU
POSTED BY; Mr. Batenchong Simon Ebaieyong. personal adviser to the president and to the association
Monday, 4 May 2015
CALCIUM DEFICIENCY
POSTED BY: Mr. Batenchong Simon Ebaieyong; Adviser to the president and association
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