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UNIVERSITY OF BUEA ONLINE STUDENT ASSOCIATION (UBOSA)
COORDINATOR: LOKENDO T. DEPT:
BIOCHEMISTRY AND MOLECULAR BIOLOGY
COURSE CODE: BCH 310
COURSE TITLE GENETICS
TUTORIAL SESSION
5
Date: Thursday 7th May 2015 Time: 8-11am
Motto: Thinking out of the box for
excellence
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1) What do you understand by each of the
following?
I.
Chromosomal aberration.
II.
Synonymous mutation.
2) What is genetics? Give importance of
genetics.
3) Distinguish between the following pairs
I.
Euchromatin and heterochromatin.
II.
Constitutive and facultative heterochromatin.
4) What do you understand by the melting point
of DNA?
5)
What is
the melting point of a double stranded DNA molecule that contains
I.
27% GC?
II.
56% GC?
6) Name the major helical conformations of
DNA.
7)
What do
you understand by major and minor grooves with respect to DNA structure?
8) What are the Watson and Crick base pairs?
Why are they important?
9) Consider the following molecules: Guanine (G);
Adenine(A); Uracil(U); Thymine(T); Cytosine(C) and the following properties:
I.
Possesses at least a hydroxyl function.
II.
Possesses an amine function.
III.
Does not contain an oxygen atom.
IV.
Possesses a methyl group
V.
Can base pair wit adenine
VI.
Is a purine base.
VII.
Is a pyrimidine base.
Associate to each molecule, the number(s)
of the property(s) that is (are) applicable to it.
10) Is the intracellular messenger cAMP a
nucleoside or a nucleotide?
11) Match the following list of scientists against
their discoveries
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Scientists
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Discoveries
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12)
Darwin and Wallace
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I.
Genes linearly arranged on some chromosomes
and mapped.
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13)
TH Morgan
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II.
Related “genes” to enzymes and biochemical
processes
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14)
Sutton Boveri
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III.
Chromosomal theory of inheritance
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15)
Gregor Mendel
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IV.
Theories of acquisition of inheritable traits
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16)
Friedrich Miescher
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V.
Theories of evolution
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17)
Beadle and Tatum
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VI.
Came up with a central dogma (DNAàmRNAàProteins)
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18)
AH Sturtevant
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VII.
Theories of transmission of traits
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19)
Oswald Avery x
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VIII.
Identified DNA in 1869
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20)
Watson, Crick, Franklin & Wilkins
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IX.
Genes on chromosomes
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21)
Lamarck
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X.
DNA was the genetic material
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22) Give one example of each mutagens and
briefly describe how it increases the rate of mutagenesis:
II.
A DNA-modifying chemical
III.
A base analog
23) a) If the GC content of a DNA molecule is
24%, what are the percentages of the four bases (A, G, C, and T) in the
molecule?
b) What is the melting temperature of this DNA?
Good Luck
“Remember,
when you read, you skim the surface, but when you study, you discover the
treasure”
